Philips Sonicare Standard E Series Brush Heads. Up to 2x better. Plaque removal vs. store brands. Up to 100% more plaque removal vs. store brand. Up to 2x better plaque removal vs. a manual toothbrush. Screw on system for: Essence xtreme elite advance. Recyclable packaging material. Developed in the U.S.A. Made by Philips in China. Protected by U.S. and international patents. Philips sonicare e series. Replacement brush head. Up to 2x better plaque removal than a manual toothbrush.